STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proPOsmosensory proline/betaine/H+ permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Glutamate family. (500 aa)    
Predicted Functional Partners:
clsB
Cardiolipin synthase 2; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
   
  
 0.739
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
   
  
 0.659
clsA
Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
   
  
 0.649
opuA
Glycine betaine ABC transporter, ATPase/permease fusion protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Amino acids, peptides and amines.
      
 0.647
proY
Proline (histidine) APC transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Glutamate family.
      
 0.647
envZ
Osmolarity sensor protein EnvZ.
      
 0.588
tauB-II
ATP-binding taurine transporter subunit; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
      
 0.518
hemB
5-aminolevulinate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Heme, porphyrin, and cobalamin; Belongs to the ALAD family.
       0.469
PP_4524
Putative Sodium-solute symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.459
rpsO
30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
      
 0.436
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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