Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PP_3024Homologs of previously reported genes of unknown function. (398 aa)    
Predicted Functional Partners:
PP_2166
Anti-anti-sigma factor.
  
 
 0.897
PP_4364
Putative Anti-sigma F factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.897
fliA
RNA polymerase sigma 28 (sigma F) factor for class III flagellar operons; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
  
 
 0.856
PP_4363
Sensor histidine kinase/response regulator.
  
 
 0.830
PP_3413
Sensor histidine kinase/response regulator.
  
  
 0.818
PP_5550
Homologs of previously reported genes of unknown function; Unknown function.
       0.814
fliG
Flagellar motor switch protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
   
    0.812
flgK
Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
   
    0.812
flgH
Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
   
    0.812
flgB
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.812
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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