STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aacsAcetoacetyl-coenzyme A synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. (650 aa)    
Predicted Functional Partners:
fadB
enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.972
mvaB
Hydroxymethylglutaryl-CoA lyase.
 
 0.950
bktB
Beta-ketothiolase BktB; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.945
hbdH
3-hydroxybutyrate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.943
hbd
3-hydroxybutyryl-CoA dehydrogenase.
  
 
 0.939
PP_3394
Putative 3-hydroxy-3-methylglutaryl-CoA lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.935
fadA
3-ketoacyl-CoA thiolase (thiolase I); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
PP_2215
acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
yqeF
acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.930
PP_0582
Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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