STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hbdH3-hydroxybutyrate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)    
Predicted Functional Partners:
aacs
Acetoacetyl-coenzyme A synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
    
 0.943
atoB
Acetoacetyl CoA-transferase (subunit B); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 0.942
atoA
Acetoacetyl CoA-transferase (subunit A); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
 
 0.939
PP_3394
Putative 3-hydroxy-3-methylglutaryl-CoA lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.903
mvaB
Hydroxymethylglutaryl-CoA lyase.
   
 
 0.903
bhbP
D-beta-hydroxybutyrate permease; Function of strongly homologous gene; transporter; Transport and binding proteins.
 
  
 0.888
iorA-II
Isoquinoline 1-oxidoreductase subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.759
PP_4452
NAD/NADP octopine/nopaline dehydrogenase family protein.
    
 
 0.751
def-II
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
      
 0.742
PP_3622
Putative Isoquinoline 1-oxidoreductase, beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.738
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.