STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroF-IITyr-sensitive phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (353 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
    
 0.923
aroH
Phospho-2-dehydro-3-deoxyheptonate aldolase.
     
 0.910
aroF-I
Tyr-sensitive phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
  
  
 
0.903
pheA
Chorismate mutase/Prephenate dehydratase; Function of strongly homologous gene; enzyme.
  
  
 0.666
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.662
ppiC-II
Peptidyl-prolyl cis-trans isomerase C (rotamase C); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinfate : Protein folding and stabilization.
  
    0.582
PP_3075
Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.542
PP_3076
Putative ABC transporter permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
  
    0.542
PP_3077
Putative ABC transporter permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
       0.542
PP_3078
Putative ABC transporter, periplasmic binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.542
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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