STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3175Putative Dioxygenase, ferredoxin reductase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (506 aa)    
Predicted Functional Partners:
PP_5371
Rubredoxin/rubredoxin reductase; Belongs to the FAD-dependent oxidoreductase family.
 
0.983
cysG
Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.912
PP_1703
Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
  
 0.786
hmp
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
  
  
 0.779
cobA
Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.744
PP_2185
Putative Formate dehydrogenase, alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.724
rubA
Rubredoxin-1.
  
 
 0.723
alkT
Rubredoxin-NAD(+) reductase; Belongs to the FAD-dependent oxidoreductase family.
 
0.708
nirD
Nitrite reductase.
 
 0.703
nirB
Nitrite reductase [NAD(P)H] large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
0.680
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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