| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_3238 | codA | PP_3238 | PP_3189 | Putative Transcriptional regulator PyrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | 0.903 |
| PP_3238 | ppnP | PP_3238 | PP_4248 | Putative Transcriptional regulator PyrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
| PP_3238 | pydA | PP_3238 | PP_4038 | Putative Transcriptional regulator PyrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | NADP-dependent dihydropyrimidine dehydrogenase subunit PreA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. | 0.947 |
| PP_3238 | pydX | PP_3238 | PP_4037 | Putative Transcriptional regulator PyrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | NADP-dependent dihydropyrimidine dehydrogenase subunit; Function of strongly homologous gene; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.900 |
| PP_3238 | pyrR | PP_3238 | PP_4997 | Putative Transcriptional regulator PyrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase; Function of strongly homologous gene; regulator. | 0.975 |
| PP_3238 | upp | PP_3238 | PP_0746 | Putative Transcriptional regulator PyrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.918 |
| PP_3662 | codA | PP_3662 | PP_3189 | Homologs of previously reported genes of unknown function; Unknown function. | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | 0.902 |
| PP_3662 | ppnP | PP_3662 | PP_4248 | Homologs of previously reported genes of unknown function; Unknown function. | Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.913 |
| codA | PP_3238 | PP_3189 | PP_3238 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | Putative Transcriptional regulator PyrR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.903 |
| codA | PP_3662 | PP_3189 | PP_3662 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | Homologs of previously reported genes of unknown function; Unknown function. | 0.902 |
| codA | codB | PP_3189 | PP_3187 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | Cytosine transporter. | 0.958 |
| codA | oplA | PP_3189 | PP_3515 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | 5-oxoprolinase A; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | 0.900 |
| codA | oplB | PP_3189 | PP_3514 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | 0.900 |
| codA | ppnP | PP_3189 | PP_4248 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
| codA | pydA | PP_3189 | PP_4038 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | NADP-dependent dihydropyrimidine dehydrogenase subunit PreA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. | 0.926 |
| codA | pydX | PP_3189 | PP_4037 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | NADP-dependent dihydropyrimidine dehydrogenase subunit; Function of strongly homologous gene; enzyme; Fattyacidandphospholipidmetabolism : Degradation. | 0.904 |
| codA | pyrR | PP_3189 | PP_4997 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase; Function of strongly homologous gene; regulator. | 0.911 |
| codA | upp | PP_3189 | PP_0746 | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.949 |
| codB | codA | PP_3187 | PP_3189 | Cytosine transporter. | Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions. | 0.958 |
| codB | upp | PP_3187 | PP_0746 | Cytosine transporter. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.488 |