Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PP_3266Homologs of previously reported genes of unknown function. (350 aa)    
Predicted Functional Partners:
ybhN
Phospholipid modification enzyme; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.900
clsB
Cardiolipin synthase 2; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  
    0.878
ybhP-I
Putative phosphohydrolase of unknown function; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biologicalprocesses : Scavenge (Catabolism).
  
    0.819
ligD
DNA ligase D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.
 
    0.805
PP_5595
Homologs of previously reported genes of unknown function; Unknown function.
       0.686
ku
Non-homologous end joining protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
    0.662
PP_3831
Homologs of previously reported genes of unknown function.
  
    0.646
PP_3241
Homologs of previously reported genes of unknown function.
  
    0.619
treZ
Malto-oligosyltrehalose trehalohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Biosynthesis and degradation of polysaccharides.
  
    0.596
PP_3267
Putative Clp protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.574
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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