| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_0354 | PP_2796 | PP_0354 | PP_2796 | CBS domain protein. | Homologs of previously reported genes of unknown function. | 0.528 |
| PP_0354 | PP_3273 | PP_0354 | PP_3273 | CBS domain protein. | Homologs of previously reported genes of unknown function. | 0.510 |
| PP_0354 | acs | PP_0354 | PP_3458 | CBS domain protein. | Butyrate--CoA ligase; Function experimentally demonstrated in the studied genus; enzyme; Fatty acid and phospholipid metabolism. | 0.759 |
| PP_0354 | acsA-I | PP_0354 | PP_4487 | CBS domain protein. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.728 |
| PP_0354 | acsA-II | PP_0354 | PP_4702 | CBS domain protein. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.780 |
| PP_0354 | actP-III | PP_0354 | PP_3272 | CBS domain protein. | Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.941 |
| PP_0354 | scpC | PP_0354 | PP_0154 | CBS domain protein. | propionyl-CoA:succinate CoA transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. | 0.857 |
| PP_0354 | yjcH | PP_0354 | PP_1742 | CBS domain protein. | Conserved inner membrane protein of unknown function; Homologs of previously reported genes of unknown function; putative membrane component; Unknown function. | 0.919 |
| PP_2796 | PP_0354 | PP_2796 | PP_0354 | Homologs of previously reported genes of unknown function. | CBS domain protein. | 0.528 |
| PP_2796 | actP-III | PP_2796 | PP_3272 | Homologs of previously reported genes of unknown function. | Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.916 |
| PP_3273 | PP_0354 | PP_3273 | PP_0354 | Homologs of previously reported genes of unknown function. | CBS domain protein. | 0.510 |
| PP_3273 | actP-III | PP_3273 | PP_3272 | Homologs of previously reported genes of unknown function. | Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.976 |
| PP_3273 | paaZ | PP_3273 | PP_3270 | Homologs of previously reported genes of unknown function. | oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | 0.651 |
| PP_3273 | phaK | PP_3273 | PP_3271 | Homologs of previously reported genes of unknown function. | Phenylacetic acid-specific porin; Function experimentally demonstrated in the studied strain; transporter; Transportandbindingproteins : Porins. | 0.731 |
| acs | PP_0354 | PP_3458 | PP_0354 | Butyrate--CoA ligase; Function experimentally demonstrated in the studied genus; enzyme; Fatty acid and phospholipid metabolism. | CBS domain protein. | 0.759 |
| acs | acsA-I | PP_3458 | PP_4487 | Butyrate--CoA ligase; Function experimentally demonstrated in the studied genus; enzyme; Fatty acid and phospholipid metabolism. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.581 |
| acs | acsA-II | PP_3458 | PP_4702 | Butyrate--CoA ligase; Function experimentally demonstrated in the studied genus; enzyme; Fatty acid and phospholipid metabolism. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.581 |
| acs | actP-III | PP_3458 | PP_3272 | Butyrate--CoA ligase; Function experimentally demonstrated in the studied genus; enzyme; Fatty acid and phospholipid metabolism. | Acetate permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.716 |
| acs | scpC | PP_3458 | PP_0154 | Butyrate--CoA ligase; Function experimentally demonstrated in the studied genus; enzyme; Fatty acid and phospholipid metabolism. | propionyl-CoA:succinate CoA transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism. | 0.837 |
| acsA-I | PP_0354 | PP_4487 | PP_0354 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | CBS domain protein. | 0.728 |