STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3312Putative Heat shock protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the small heat shock protein (HSP20) family. (129 aa)    
Predicted Functional Partners:
PP_3314
Heat shock protein, HSP20 family; Belongs to the small heat shock protein (HSP20) family.
 
  
 0.979
PP_3316
Putative Chaperone-associated ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the ClpA/ClpB family.
 
 
 0.788
PP_3313
Putative Heat shock protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the small heat shock protein (HSP20) family.
 
  
0.716
clpS
ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
   
  
 0.698
ibpA
Small heat shock protein IbpA; Function of homologous gene experimentally demonstrated in an other organism; factor; Cellularprocesses : Adaptations to atypical conditions; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.625
clpB
Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA/ClpB family.
 
 
 0.605
clpA
ATP-dependent serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides; Belongs to the ClpA/ClpB family.
 
 
 0.594
clpV
Protein ClpV1; Belongs to the ClpA/ClpB family.
 
 
 0.592
kefB-II
Glutathione-regulated potassium/H+ antiporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.501
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.486
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.