STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3328Putative Ring-cleaving dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (137 aa)    
Predicted Functional Partners:
PP_1239
Metallo-beta-lactamase family protein.
      
 0.879
mrcA
Penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase; Function of strongly homologous gene; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan.
      
 0.836
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
      
 0.642
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  
 0.589
PP_5599
Putative transcriptional regulator, LysR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions; Belongs to the LysR transcriptional regulatory family.
       0.573
PP_3329
Homologs of previously reported genes of unknown function.
  
    0.493
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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