Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_3350Homologs of previously reported genes of unknown function. (463 aa)    
Predicted Functional Partners:
PP_1061
Putative ATP-dependent DNA helicase lhr; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
   
 0.801
kefB-III
Glutathione-regulated potassium/H+ antiporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.768
PP_5245
Transcriptional regulator, AraC family.
      
 0.766
PP_1060
Putative Glutamate synthase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the glutamate synthase family.
      
 0.744
PP_5252
Homologs of previously reported genes of unknown function.
 
     0.743
ttgB
Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.707
ribC
Riboflavin synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Riboflavin, FMN, and FAD.
      
 0.706
mhpT
3-hydroxyphenylpropionate / 3-hydroxycinnamate:H+ symporter; Function of strongly homologous gene; transporter; Fattyacidandphospholipidmetabolism : Degradation.
       0.676
PP_3976
Hydrolase, isochorismatase family.
 
     0.658
yadG
Putative ABC transporter - ATP binding subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
      
 0.651
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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