| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_3361 | PP_3362 | PP_3361 | PP_3362 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Transcriptional regulator, AsnC family. | 0.680 |
| PP_3361 | bdhA | PP_3361 | PP_0552 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | 0.786 |
| PP_3361 | nicA | PP_3361 | PP_3947 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Nicotinate dehydrogenase subunit A; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). | 0.853 |
| PP_3361 | nicB | PP_3361 | PP_3948 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Nicotinate dehydrogenase subunit B; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). | 0.767 |
| PP_3361 | nicC | PP_3361 | PP_3944 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. | 0.775 |
| PP_3361 | nicP-II | PP_3361 | PP_3939 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Porin-like protein; Probable transporter, possibly involved in the aerobic nicotinate degradation pathway; Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. | 0.860 |
| PP_3361 | nicT | PP_3361 | PP_3940 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Putative metabolite transport protein NicT; Probable transporter, possibly involved in the aerobic nicotinate degradation pathway. | 0.864 |
| PP_3361 | polA | PP_3361 | PP_0123 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | DNA polymerase I, 5' -> 3' polymerase with 5' --> 3' and 3' --> 5' exonuclease activity; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.615 |
| PP_3361 | ramA | PP_3361 | PP_3846 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | (R)-stereoselective amidase. | 0.920 |
| PP_3361 | rpoZ | PP_3361 | PP_5301 | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.718 |
| PP_3362 | PP_3361 | PP_3362 | PP_3361 | Transcriptional regulator, AsnC family. | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.680 |
| bdhA | PP_3361 | PP_0552 | PP_3361 | 2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.786 |
| bdhA | nicA | PP_0552 | PP_3947 | 2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | Nicotinate dehydrogenase subunit A; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). | 0.434 |
| bdhA | nicC | PP_0552 | PP_3944 | 2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. | 0.491 |
| bdhA | nicP-II | PP_0552 | PP_3939 | 2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | Porin-like protein; Probable transporter, possibly involved in the aerobic nicotinate degradation pathway; Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. | 0.486 |
| bdhA | nicT | PP_0552 | PP_3940 | 2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | Putative metabolite transport protein NicT; Probable transporter, possibly involved in the aerobic nicotinate degradation pathway. | 0.536 |
| bdhA | ramA | PP_0552 | PP_3846 | 2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | (R)-stereoselective amidase. | 0.804 |
| nicA | PP_3361 | PP_3947 | PP_3361 | Nicotinate dehydrogenase subunit A; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). | Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.853 |
| nicA | bdhA | PP_3947 | PP_0552 | Nicotinate dehydrogenase subunit A; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). | 2,3-butanediol dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism). | 0.434 |
| nicA | nicB | PP_3947 | PP_3948 | Nicotinate dehydrogenase subunit A; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). | Nicotinate dehydrogenase subunit B; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA). | 0.999 |