Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_3394Putative 3-hydroxy-3-methylglutaryl-CoA lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (309 aa)    
Predicted Functional Partners:
liuC
methylglutaconyl-CoA hydratase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.979
PP_3393
CAIB/BAIF family protein; Belongs to the CoA-transferase III family.
 
  0.957
atoA
Acetoacetyl CoA-transferase (subunit A); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
  
 
 0.942
atoB
Acetoacetyl CoA-transferase (subunit B); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
  
 
 0.937
aacs
Acetoacetyl-coenzyme A synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
 
 0.936
PP_2215
acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.933
PP_0582
Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
fadA
3-ketoacyl-CoA thiolase (thiolase I); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
pcaF-II
Beta-ketoadipyl CoA thiolase, beta component; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
 
 0.929
PP_3355
Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.929
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (50%) [HD]