STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alkBAlpha-ketoglutarate- and Fe(II)-dependent dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : Restriction/modification. (215 aa)    
Predicted Functional Partners:
ada
Fused O(6)-alkylguanine DNA alkyltransferase - transcriptional activator; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.
  
 0.976
alkT
Rubredoxin-NAD(+) reductase; Belongs to the FAD-dependent oxidoreductase family.
     
 0.899
rubA
Rubredoxin-1.
      
 0.866
PP_0705
DNA-3-methyladenine glycosylase.
     
 0.855
calB
Coniferyl aldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the aldehyde dehydrogenase family.
      
 0.850
ogt
O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.836
PP_5372
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
      
 0.820
aldB-II
Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family.
      
 0.818
aldB-I
Aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the aldehyde dehydrogenase family.
      
 0.814
aldA
Putative aldehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aldehyde dehydrogenase family.
      
 0.812
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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