Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_3415Transcriptional regulator, LacI family. (339 aa)    
Predicted Functional Partners:
fruB
Phosphotransferase system, fructose-specific EI/HPr/EIIA components; Function experimentally demonstrated in the studied genus; transporter; Energymetabolism : Sugars; Belongs to the PEP-utilizing enzyme family.
 
 
 
 0.914
kguK
Putative 2-ketogluconokinase; Function experimentally demonstrated in the studied genus; putative enzyme; Energy metabolism.
 
  
 0.836
gnuK
D-gluconate kinase; Function experimentally demonstrated in the studied strain; enzyme.
 
 
 0.834
PP_0652
Gluconate transporter.
  
  
 0.816
gltB
L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family.
    
 
 0.763
kguT
2-ketogluconate transporter, putative; Function experimentally demonstrated in the studied genus; transporter; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids.
   
  
 0.748
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.671
PP_2761
Putative Ribose ABC transporter, permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.647
hexR
DNA-binding transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region.
  
   
 0.626
fruA
Fructose PTS permease - IIBC component; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energy metabolism.
 
   
 0.607
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (28%) [HD]