Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gnuKD-gluconate kinase; Function experimentally demonstrated in the studied strain; enzyme. (179 aa)    
Predicted Functional Partners:
gntZ
Putative 6-phosphogluconate dehydrogenase, decarboxylating; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.995
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
  
 
 0.986
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
  
 
 0.979
PP_3384
Gluconate 2-dehydrogenase gamma subunit; Function of strongly homologous gene; enzyme; Energy metabolism.
     
 0.961
PP_3383
Gluconate 2-dehydrogenase flavoprotein subunit; Function experimentally demonstrated in the studied genus; enzyme; Energy metabolism.
     
 0.937
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.929
ppgL
L-alpha-hydroxyglutaric acid gamma-lactonase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
     
 0.904
ghrB
2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.903
ptxD
Putative phosphonate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Centralintermediarymetabolism : Phosphorus compounds; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.903
kguK
Putative 2-ketogluconokinase; Function experimentally demonstrated in the studied genus; putative enzyme; Energy metabolism.
 
   
 0.900
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.