Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_3419Sigma-54 dependent transcriptional regulator/response regulator. (475 aa)    
Predicted Functional Partners:
PP_3420
Sensor histidine kinase.
 
 
 0.908
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
  
 0.820
PP_3421
Sensor histidine kinase.
 
 
 0.794
glnL
Two-component system sensory histidine kinase/phosphatase GlnL/GlnG; Function of homologous gene experimentally demonstrated in an other organism; receptor; Centralintermediarymetabolism : Nitrogen metabolism.
 
 0.650
PP_4342
Flagellar synthesis regulator, putative ATPase; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
 
 0.605
PP_4959
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
  
 
 0.604
fliM
Flagellar synthesis, switching and energizing component; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.462
flhF
Flagellar biosynthesis protein FlhF.
  
  
 0.461
fliP
Flagellar export apparatus subunit; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
  
 0.447
fliE
Flagellar hook-basal body complex protein FliE.
  
  
 0.447
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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