Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PP_3420Sensor histidine kinase. (497 aa)    
Predicted Functional Partners:
PP_3419
Sigma-54 dependent transcriptional regulator/response regulator.
 
 
 0.908
PP_2810
Homologs of previously reported genes of unknown function.
      
 0.864
PP_2813
BNR domain protein.
      
 0.859
PP_3009
Homologs of previously reported genes of unknown function.
   
  
 0.857
PP_3656
Putative Aromatic compound-specific porin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.853
PP_4643
Xanthine/uracil permease family protein.
      
 0.851
PP_3484
Response regulator receiver protein.
  
   0.813
PP_4824
Sensor histidine kinase/response regulator.
 
   0.780
PP_3833
Response regulator.
 
   0.767
PP_1651
Two-component response regulator; Function of strongly homologous gene; regulator; Regulatory functions.
 
   0.763
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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