Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PP_3447Homologs of previously reported genes of unknown function. (143 aa)    
Predicted Functional Partners:
PP_4156
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
 
   
 0.588
PP_2250
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.580
PP_3451
Homologs of previously reported genes of unknown function.
  
    0.507
nfrB
Bacteriophage N4 receptor, inner membrane subunit; Function of homologous gene experimentally demonstrated in an other organism; phenotype; Unknown function.
  
    0.503
PP_3449
Homologs of previously reported genes of unknown function.
  
    0.503
PP_3513
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
 
   
 0.501
PP_3450
Conserved protein of unknown function containing TPR repeat; Homologs of previously reported genes of unknown function; Unknown function.
       0.499
ilvA-I
Threonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.477
PP_3438
Homologs of previously reported genes of unknown function.
  
     0.403
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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