Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_3454Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions. (233 aa)    
Predicted Functional Partners:
PP_3453
Putative Sensor protein RstB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.995
PP_1182
Sensor histidine kinase.
 
 
 0.839
pfeS-I
Histidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.826
pfeS-II
Histidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.817
PP_4505
Sensor histidine kinase.
 
 
 0.815
PP_1437
Heavy metal sensor histidine kinase; Member of a two-component regulatory system.
 
 
 0.813
czrSA
Metal-sensor histidine kinase; Member of a two-component regulatory system.
 
 
 0.807
PP_3371
Sensor histidine kinase.
 
 
 0.806
PP_0270
Sensor histidine kinase.
 
 
 0.798
PP_3728
Sensor histidine kinase/response regulator.
 
 
 0.797
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.