STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3455Multidrug efflux RND membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (391 aa)    
Predicted Functional Partners:
mexB
Multidrug resistance protein MexB.
 0.996
ttgB
Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 0.991
ttgC
Probable efflux pump outer membrane protein TtgC; Probable outer membrane component of the TtgABC efflux pump with unknown specificity; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 0.975
PP_0906
Putative Multidrug efflux RND transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 0.966
PP_4923
Outer membrane efflux protein.
 
 0.941
PP_1798
Outer membrane efflux protein.
  
 0.929
ttgA
Probable efflux pump periplasmic linker TtgA; Probable periplasmic linker protein component of the TtgABC efflux pump with unknown specificity; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 
0.908
PP_0907
RND efflux membrane fusion protein-related protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 
0.907
mexF
Multidrug efflux RND transporter MexF.
 
 0.898
pvdT
Pyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.891
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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