Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PP_3491Enoly-coenzyme A hydratase/isomerase family protein. (357 aa)    
Predicted Functional Partners:
mmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
 0.982
PP_3925
Homologs of previously reported genes of unknown function.
   
 
 0.882
PP_3492
Short-chain acyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
  
 0.861
hbd
3-hydroxybutyryl-CoA dehydrogenase.
 0.729
PP_4817
MaoC domain protein.
  
 0.694
PP_0580
MaoC domain protein.
  
 0.691
PP_4552
Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.663
PP_2047
3-hydroxyacyl-CoA dehydrogenase family protein.
 0.644
PP_2540
Oxidoreductase, short-chain dehydrogenase/reductase family.
  
 0.642
PP_2979
Homologs of previously reported genes of unknown function.
      
 0.634
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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