| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_3509 | PP_3510 | PP_3509 | PP_3510 | Glyoxalase family protein. | Homologs of previously reported genes of unknown function. | 0.782 |
| PP_3509 | birA | PP_3509 | PP_0437 | Glyoxalase family protein. | Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.454 |
| PP_3509 | ilvE | PP_3509 | PP_3511 | Glyoxalase family protein. | Branched-chain-amino-acid aminotransferase. | 0.492 |
| PP_3509 | nuoC | PP_3509 | PP_4121 | Glyoxalase family protein. | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.494 |
| PP_3509 | nuoI | PP_3509 | PP_4126 | Glyoxalase family protein. | NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.429 |
| PP_3509 | sdhC | PP_3509 | PP_4193 | Glyoxalase family protein. | Succinate dehydrogenase membrane b-556 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic. | 0.420 |
| PP_3509 | tadA | PP_3509 | PP_1035 | Glyoxalase family protein. | tRNA-specific adenosine deaminase monomer; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.429 |
| PP_3509 | yfhL | PP_3509 | PP_5124 | Glyoxalase family protein. | Putative 4Fe-4S cluster-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; carrier; Energymetabolism : Electron transport. | 0.429 |
| PP_3510 | PP_3509 | PP_3510 | PP_3509 | Homologs of previously reported genes of unknown function. | Glyoxalase family protein. | 0.782 |
| PP_3510 | ilvE | PP_3510 | PP_3511 | Homologs of previously reported genes of unknown function. | Branched-chain-amino-acid aminotransferase. | 0.483 |
| birA | PP_3509 | PP_0437 | PP_3509 | Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Glyoxalase family protein. | 0.454 |
| birA | ilvE | PP_0437 | PP_3511 | Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Branched-chain-amino-acid aminotransferase. | 0.425 |
| birA | nuoC | PP_0437 | PP_4121 | Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.618 |
| birA | tadA | PP_0437 | PP_1035 | Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA-specific adenosine deaminase monomer; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.923 |
| ilvE | PP_3509 | PP_3511 | PP_3509 | Branched-chain-amino-acid aminotransferase. | Glyoxalase family protein. | 0.492 |
| ilvE | PP_3510 | PP_3511 | PP_3510 | Branched-chain-amino-acid aminotransferase. | Homologs of previously reported genes of unknown function. | 0.483 |
| ilvE | birA | PP_3511 | PP_0437 | Branched-chain-amino-acid aminotransferase. | Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.425 |
| ilvE | nuoC | PP_3511 | PP_4121 | Branched-chain-amino-acid aminotransferase. | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.590 |
| nuoC | PP_3509 | PP_4121 | PP_3509 | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Glyoxalase family protein. | 0.494 |
| nuoC | birA | PP_4121 | PP_0437 | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.618 |