STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaBHydroxymethylglutaryl-CoA lyase. (299 aa)    
Predicted Functional Partners:
PP_3539
Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.986
liuC
methylglutaconyl-CoA hydratase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.982
aacs
Acetoacetyl-coenzyme A synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
 
 0.950
atoB
Acetoacetyl CoA-transferase (subunit B); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
  
 
 0.935
atoA
Acetoacetyl CoA-transferase (subunit A); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
  
 
 0.933
PP_2215
acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.927
fadA
3-ketoacyl-CoA thiolase (thiolase I); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
paaJ
3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
PP_3355
Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
PP_0582
Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.920
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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