STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PP_3547Putative NAD(P)-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. (313 aa)    
Predicted Functional Partners:
panE
Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
      
 0.760
nuoC
NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.725
fdx
Ferredoxin; Function of homologous gene experimentally demonstrated in an other organism; carrier; Energymetabolism : Electron transport.
   
 
 0.709
PP_0429
Oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 
 0.591
PP_1274
Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.535
PP_4379
Beta-ketoacyl-acyl-carrier-protein synthase I.
  
  
 0.519
PP_2989
Oxidoreductase, short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 
 0.465
betC
Choline-sulfatase; Function experimentally demonstrated in the studied strain; enzyme; Central intermediary metabolism.
   
 
 0.460
atsA
Arylsulfatase; Function experimentally demonstrated in the studied genus; enzyme; Centralintermediarymetabolism : Sulfur metabolism.
   
 
 0.460
fabD
malonyl-CoA-ACP transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis.
 
 
 0.440
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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