STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3581Homologs of previously reported genes of unknown function. (695 aa)    
Predicted Functional Partners:
PP_2739
Putative Sensory box protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.918
PP_4629
Sensory box protein.
 
      0.883
PP_2505
GAF domain/GGDEF domain protein.
 
0.858
PP_4642
Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
      
 0.834
PP_1154
Sensory box protein.
 
 
0.763
PP_2945
Putative sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
 0.759
yegE
Diguanylate cyclase with phosphodiesterase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Proteinfate : Protein modification and repair.
 
 
0.746
PP_3711
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
 
 
0.738
PP_3761
Sensor histidine kinase/response regulator.
 
  
 0.728
PP_0672
Sensory box protein.
 
 
0.709
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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