STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htrGPutative signal transduction protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (216 aa)    
Predicted Functional Partners:
cca
tRNA nucleotidyltransferase - 2',3'-cyclic phosphodiesterase - 2' nucleotidase and phosphatase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
 
  
 0.735
plsB
Glycerol-3-phosphate acyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis; Belongs to the GPAT/DAPAT family.
  
    0.518
PP_0973
Nucleoid-associated protein PP_0973.
  
     0.497
PP_1368
Putative membrane protein containing a glycosyltransferase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
  
     0.485
PP_2745
Universal stress protein family.
 
    0.442
PP_3082
Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
   
 0.442
opdT-II
Tyrosine-specific outer membrane porin D; Function experimentally demonstrated in the studied genus; transporter.
       0.433
PP_3143
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.409
PP_4918
Homologs of previously reported genes of unknown function.
  
    0.401
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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