Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_3654Leucine-responsive regulatory protein; Function of homologous gene experimentally demonstrated in an other organism; regulator. (150 aa)    
Predicted Functional Partners:
opgH
Glucans biosynthesis glucosyltransferase H; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
      
 0.765
PP_3653
Transporter, LysE family.
 
     0.668
PP_1446
TonB-dependent receptor.
      
 0.655
PP_2676
Putative Periplasmic binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.654
parB
Probable chromosome-partitioning protein; Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity).
      
 0.549
mdeA
Methionine gamma-lyase; Function experimentally demonstrated in the studied strain; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
     
 0.532
gltB
L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family.
     
 0.517
phhB
Pterin-4-alpha-carbinolamine dehydratase; Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. May also have a positive regulatory role in the expression of phhA (By similarity); Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
     
 0.508
phhA
Phenylalanine-4-hydroxylase; Function experimentally demonstrated in the studied strain; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
     
 0.441
phhR
Sigma-54 dependent transcriptional regulator; Function experimentally demonstrated in the studied strain; regulator; Fattyacidandphospholipidmetabolism : Degradation.
      
 0.427
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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