STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3662Homologs of previously reported genes of unknown function; Unknown function. (457 aa)    
Predicted Functional Partners:
yrfG
Purine nucleotidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
  0.915
ppnP
Conserved protein of unknown function, UPF0345 family; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
  
 
  0.913
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
   
 
 0.913
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.905
surE
5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.904
Nuh
Ribonucleoside hydrolase; Function experimentally demonstrated in the studied strain; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions; Belongs to the IUNH family.
  
 
  0.904
purB
5'-phosphoribosyl-4-(N-succinocarboxamide)-5- aminoimidazole lyase (adenylosuccinate lyase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Purine ribonucleotide biosynthesis; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
  0.904
pde
3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
 
  0.903
codA
Cytosine deaminase / isoguanine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions.
    
  0.902
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
  0.901
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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