STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3689Putative Serine/threonine protein phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (335 aa)    
Predicted Functional Partners:
PP_2431
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
   
  
 0.831
asd-2
Aspartate-semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Aminoacidbiosynthesis : Aspartate family; Belongs to the aspartate-semialdehyde dehydrogenase family.
      
 0.646
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
   
  
 0.522
yhhS
Carbohydrate efflux transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins.
  
   
 0.503
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
     
 0.492
PP_5395
Homologs of previously reported genes of unknown function.
  
  
 0.490
PP_1834
Homologs of previously reported genes of unknown function.
   
 
 0.477
PP_5065
Homologs of previously reported genes of unknown function.
   
 
 0.477
gsiA
Glutathione ABC transporter ATP-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins; Belongs to the ABC transporter superfamily.
     
 0.457
PP_3453
Putative Sensor protein RstB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  
 0.444
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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