Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_3689Putative Serine/threonine protein phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (335 aa)    
Predicted Functional Partners:
PP_3912
DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.869
PP_3989
DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.869
PP_2431
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
   
  
 0.819
yafJ
Putative amidotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
     
 0.602
PP_5395
Homologs of previously reported genes of unknown function.
  
  
 0.490
PP_5126
Conserved protein of unknown function containing an HDOD domain; Homologs of previously reported genes of unknown function; Unknown function.
      
 0.465
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
     
 0.450
PP_1987
Methlytransferase, UbiE/COQ5 family.
  
    0.445
asd-2
Aspartate-semialdehyde dehydrogenase; Function of strongly homologous gene; enzyme; Aminoacidbiosynthesis : Aspartate family; Belongs to the aspartate-semialdehyde dehydrogenase family.
      
 0.437
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
   
  
 0.423
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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