STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3700Putative ATPases involved in chromosome partitioning; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. (368 aa)    
Predicted Functional Partners:
cspA-II
Nucleic acid cold-shock chaperone; Function of homologous gene experimentally demonstrated in an other organism; factor; Transcription.
   
  
 0.745
PP_1209
Cold-shock protein; Function of strongly homologous gene; factor; Biologicalprocesses : Control.
   
  
 0.739
parB
Probable chromosome-partitioning protein; Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity).
  
 
 0.682
capB
Cold shock protein CapB.
   
  
 0.652
cspA-I
Major cold shock protein; Function of homologous gene experimentally demonstrated in an other organism; factor; Transcription.
   
  
 0.649
cspD
DNA replication inhibitor; Function of homologous gene experimentally demonstrated in an other organism; regulator; DNAmetabolism : DNA replication, recombination, and repair.
   
  
 0.601
birA
Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.515
PP_3701
Homologs of previously reported genes of unknown function.
  
    0.494
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.473
PP_3702
Homologs of previously reported genes of unknown function.
  
    0.472
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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