Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
PP_3731Transcriptional regulator, TetR family. (214 aa)    
Predicted Functional Partners:
PP_3728
Sensor histidine kinase/response regulator.
   
 
 0.614
PP_3729
Periplasmic amino acid-binding protein-related protein.
   
   0.587
betA-II
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
  
 0.569
aruR
Transcriptional regulatory protein AruR.
       0.568
PP_3732
Enoyl-CoA hydratase/isomerase family protein.
       0.538
betA-I
Choline dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.522
PP_1949
Oxidoreductase, GMC family.
 
  
 0.514
PP_2824
Transcriptional regulator, TetR family.
  
     0.465
PP_1394
Putative Acetolactate synthase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the TPP enzyme family.
 
     0.435
cbcX
Choline / betaine / carnitine ABC transporter - substrate binding protein; Function experimentally demonstrated in the studied genus; transporter.
 
     0.434
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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