Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_3734Putative ABC transporter, permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (819 aa)    
Predicted Functional Partners:
PP_3735
ABC transporter ATP-binding protein.
 
 
 0.987
PP_3733
Putative ABC transporter lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    0.971
pvdT
Pyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.763
lolA
Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.714
PP_0507
Putative ABC efflux transporter, ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.690
lolD
Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 
 0.690
lolB
Outer-membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
    
 
 0.581
PP_1503
Homologs of previously reported genes of unknown function.
    
 
 0.432
vanB
Vanillate O-demethylase oxidoreductase; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism).
  
    0.430
vanA
Vanillate O-demethylase oxygenase subunit; Function experimentally demonstrated in the studied species; enzyme; Biologicalprocesses : Scavenge (Catabolism).
       0.423
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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