PP_3792 protein (Pseudomonas putida KT2440) - STRING interaction network

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[Homology]

Score

PP_3792

Homologs of previously reported genes of unknown function. (44 aa)

Predicted Functional Partners:

recA

0.706

PP_3117

0.698

polB

0.685

dnaN

0.659

lexA-I

0.626

lexA-II

0.626

polA

0.504

dnaEA

0.469

dnaEB

0.469

PP_0705

0.439

Your Current Organism:

Pseudomonas putida KT2440

NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PP_0705	PP_3792	PP_0705	PP_3792	DNA-3-methyladenine glycosylase.	Homologs of previously reported genes of unknown function.	0.439
PP_0705	polA	PP_0705	PP_0123	DNA-3-methyladenine glycosylase.	DNA polymerase I, 5' -> 3' polymerase with 5' --> 3' and 3' --> 5' exonuclease activity; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.525
PP_0705	polB	PP_0705	PP_2393	DNA-3-methyladenine glycosylase.	DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.	0.475
PP_0705	recA	PP_0705	PP_1629	DNA-3-methyladenine glycosylase.	Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.541
PP_3117	PP_3792	PP_3117	PP_3792	Putative protein involved in error-prone processing of DNA lesions; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; DNAmetabolism : DNA replication, recombination, and repair.	Homologs of previously reported genes of unknown function.	0.698
PP_3117	dnaEA	PP_3117	PP_1606	Putative protein involved in error-prone processing of DNA lesions; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; DNAmetabolism : DNA replication, recombination, and repair.	DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.	0.557
PP_3117	dnaEB	PP_3117	PP_3119	Putative protein involved in error-prone processing of DNA lesions; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; DNAmetabolism : DNA replication, recombination, and repair.	Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	0.989
PP_3117	lexA-I	PP_3117	PP_2143	Putative protein involved in error-prone processing of DNA lesions; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; DNAmetabolism : DNA replication, recombination, and repair.	Transcriptional repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.798
PP_3117	lexA-II	PP_3117	PP_3116	Putative protein involved in error-prone processing of DNA lesions; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; DNAmetabolism : DNA replication, recombination, and repair.	Transcriptional repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.941
PP_3792	PP_0705	PP_3792	PP_0705	Homologs of previously reported genes of unknown function.	DNA-3-methyladenine glycosylase.	0.439
PP_3792	PP_3117	PP_3792	PP_3117	Homologs of previously reported genes of unknown function.	Putative protein involved in error-prone processing of DNA lesions; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; DNAmetabolism : DNA replication, recombination, and repair.	0.698
PP_3792	dnaEA	PP_3792	PP_1606	Homologs of previously reported genes of unknown function.	DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.	0.469
PP_3792	dnaEB	PP_3792	PP_3119	Homologs of previously reported genes of unknown function.	Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	0.469
PP_3792	dnaN	PP_3792	PP_0011	Homologs of previously reported genes of unknown function.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.659
PP_3792	lexA-I	PP_3792	PP_2143	Homologs of previously reported genes of unknown function.	Transcriptional repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.626
PP_3792	lexA-II	PP_3792	PP_3116	Homologs of previously reported genes of unknown function.	Transcriptional repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.626
PP_3792	polA	PP_3792	PP_0123	Homologs of previously reported genes of unknown function.	DNA polymerase I, 5' -> 3' polymerase with 5' --> 3' and 3' --> 5' exonuclease activity; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.504
PP_3792	polB	PP_3792	PP_2393	Homologs of previously reported genes of unknown function.	DNA polymerase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.	0.685
PP_3792	recA	PP_3792	PP_1629	Homologs of previously reported genes of unknown function.	Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.706
dnaEA	PP_3117	PP_1606	PP_3117	DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair.	Putative protein involved in error-prone processing of DNA lesions; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; DNAmetabolism : DNA replication, recombination, and repair.	0.557