| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_1105 | PP_3831 | PP_1105 | PP_3831 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Homologs of previously reported genes of unknown function. | 0.702 |
| PP_1105 | ku | PP_1105 | PP_3255 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Non-homologous end joining protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.627 |
| PP_1105 | ligD | PP_1105 | PP_3260 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA ligase D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair. | 0.723 |
| PP_3266 | PP_3831 | PP_3266 | PP_3831 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.645 |
| PP_3266 | ku | PP_3266 | PP_3255 | Homologs of previously reported genes of unknown function. | Non-homologous end joining protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.652 |
| PP_3266 | ligD | PP_3266 | PP_3260 | Homologs of previously reported genes of unknown function. | DNA ligase D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair. | 0.791 |
| PP_3831 | PP_1105 | PP_3831 | PP_1105 | Homologs of previously reported genes of unknown function. | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.702 |
| PP_3831 | PP_3266 | PP_3831 | PP_3266 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.645 |
| PP_3831 | gyrB | PP_3831 | PP_0013 | Homologs of previously reported genes of unknown function. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.752 |
| PP_3831 | ku | PP_3831 | PP_3255 | Homologs of previously reported genes of unknown function. | Non-homologous end joining protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.740 |
| PP_3831 | ligD | PP_3831 | PP_3260 | Homologs of previously reported genes of unknown function. | DNA ligase D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNAmetabolism : DNA replication, recombination, and repair. | 0.827 |
| PP_3831 | modA | PP_3831 | PP_3828 | Homologs of previously reported genes of unknown function. | Molybdate-binding periplasmic protein. | 0.645 |
| PP_3831 | modB | PP_3831 | PP_3829 | Homologs of previously reported genes of unknown function. | Molybdenum transport system permease protein ModB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.645 |
| PP_3831 | parE | PP_3831 | PP_4915 | Homologs of previously reported genes of unknown function. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.752 |
| PP_3831 | recQ | PP_3831 | PP_4516 | Homologs of previously reported genes of unknown function. | ATP-dependent DNA 3' to 5' helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNA metabolism. | 0.781 |
| PP_3831 | rnhB | PP_3831 | PP_1605 | Homologs of previously reported genes of unknown function. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.683 |
| gyrB | PP_3831 | PP_0013 | PP_3831 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Homologs of previously reported genes of unknown function. | 0.752 |
| gyrB | recQ | PP_0013 | PP_4516 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | ATP-dependent DNA 3' to 5' helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; DNA metabolism. | 0.525 |
| ku | PP_1105 | PP_3255 | PP_1105 | Non-homologous end joining protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.627 |
| ku | PP_3266 | PP_3255 | PP_3266 | Non-homologous end joining protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | Homologs of previously reported genes of unknown function. | 0.652 |