Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_3849Putative calcium-binding protein, hemolysin-type; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; carrier; Cellular processes. (656 aa)    
Predicted Functional Partners:
PP_3920
Putative Phage integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.
      
 0.970
PP_4924
Serine protease, subtilase family.
  
0.937
cyaB
Cyclolysin secretion/processing ATP-binding protein CyaB.
 
  
 0.834
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...]
      
 0.819
PP_4926
HlyD family secretion protein.
 
  
 0.794
prtN
Transcription regulatory protein PrtN.
   
  
 0.769
PP_1797
HlyD family secretion protein.
 
  
 0.756
PP_1105
Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.740
aprDA
Alkaline protease secretion transporter ATP-binding protein; Function experimentally demonstrated in the studied genus; transporter.
 
 
 0.740
hasE
Metalloprotease secretion protein.
 
  
 0.739
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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