STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nicP-IIPorin-like protein; Probable transporter, possibly involved in the aerobic nicotinate degradation pathway; Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. (430 aa)    
Predicted Functional Partners:
PP_3889
Putative Phage integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.
  
  
 0.886
nicT
Putative metabolite transport protein NicT; Probable transporter, possibly involved in the aerobic nicotinate degradation pathway.
  
  
 0.862
PP_3361
Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
   
  
 0.831
nicC
6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family.
     
 0.806
nicB
Nicotinate dehydrogenase subunit B; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA).
      
 0.788
ramA
(R)-stereoselective amidase.
      
 0.740
PP_3733
Putative ABC transporter lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.677
nicA
Nicotinate dehydrogenase subunit A; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA).
      
 0.671
PP_3404
Homologs of previously reported genes of unknown function.
  
     0.545
PP_0886
Homologs of previously reported genes of unknown function.
  
     0.532
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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