Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tusDSulfur transfer protein complex, TusD subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Centralintermediarymetabolism : Sulfur metabolism. (130 aa)    
Predicted Functional Partners:
PP_3994
Putative tRNA 5-methylaminomethyl-2-thiouridine synthase (tusC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Centralintermediarymetabolism : Sulfur metabolism; Belongs to the DsrF/TusC family.
 
 0.999
PP_3995
Homologs of previously reported genes of unknown function.
 
 0.999
tusE
Sulfur transfer protein; Part of a sulfur-relay system.
 
 
 0.999
tusA-II
Sulfurtransferase; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
 
 
 0.998
tusA-I
Sulfurtransferase; Function of strongly homologous gene; enzyme; Belongs to the sulfur carrier protein TusA family.
 
 
 0.972
PP_3997
Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    0.944
mnmA
tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
     
 0.907
ttcA
tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
      
 0.868
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.832
iscS-I
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
    
 0.773
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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