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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_3997Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (333 aa)    
Predicted Functional Partners:
tusD
Sulfur transfer protein complex, TusD subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Centralintermediarymetabolism : Sulfur metabolism.
 
    0.911
PP_3994
Putative tRNA 5-methylaminomethyl-2-thiouridine synthase (tusC-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Centralintermediarymetabolism : Sulfur metabolism; Belongs to the DsrF/TusC family.
 
    0.892
tusE
Sulfur transfer protein; Part of a sulfur-relay system.
 
    0.892
pabB
Aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Folic acid.
 
 
 0.885
PP_3995
Homologs of previously reported genes of unknown function.
  
    0.873
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
  
 
 0.862
trpC
Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
  
 0.841
trpF
N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
  
 0.840
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.839
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.829
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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