Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_4017Homologs of previously reported genes of unknown function. (390 aa)    
Predicted Functional Partners:
PP_4018
Acetyltransferase, GNAT family.
       0.869
hflD
HflD-like high frequency lysogenization protein; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transport and binding proteins.
 
  
 0.789
purB
5'-phosphoribosyl-4-(N-succinocarboxamide)-5- aminoimidazole lyase (adenylosuccinate lyase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines,pyrimidines,nucleosides,andnucleotides : Purine ribonucleotide biosynthesis; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.787
mnmA
tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
     
 0.746
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
    
 
 0.674
nudJ
MutT/nudix family protein; Belongs to the Nudix hydrolase family. NudJ subfamily.
  
    0.637
idh
Isocitrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the monomeric-type IDH family.
       0.581
PP_0941
Putative ribosome associated protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Transport and binding proteins; Belongs to the UPF0307 family.
  
     0.546
PP_5159
Homologs of previously reported genes of unknown function.
 
     0.515
PP_4115
Homologs of previously reported genes of unknown function.
       0.488
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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