Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
zwfBGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (501 aa)    
Predicted Functional Partners:
gntZ
Putative 6-phosphogluconate dehydrogenase, decarboxylating; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.999
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 0.995
glk
Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.
 
 0.987
pgi-I
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.978
pgi-II
Glucose-6-phosphate isomerase; Function of strongly homologous gene; enzyme.
  
 
 0.973
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
  
 0.965
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Entner-Doudoroff; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.962
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 
 0.936
eda
KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff.
 
  
 0.933
pykA
Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.
  
 
 0.929
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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