| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_0101 | chrR | PP_0101 | PP_4138 | Putative sulfate transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | 0.710 |
| PP_0718 | chrR | PP_0718 | PP_4138 | Sulfate transporter. | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | 0.710 |
| PP_1407 | chrR | PP_1407 | PP_4138 | Sulfate transporter. | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | 0.710 |
| PP_2556 | arsH | PP_2556 | PP_2715 | Chromate transporter. | ArsH protein. | 0.499 |
| PP_2556 | chrR | PP_2556 | PP_4138 | Chromate transporter. | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | 0.776 |
| PP_3006 | chrR | PP_3006 | PP_4138 | RNA polymerase sigma-70 factor, ECF subfamily. | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | 0.719 |
| PP_3720 | azoR2 | PP_3720 | PP_4538 | Putative NAD(P)H quinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | FMN-dependent NADH-azoreductase 2; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. | 0.489 |
| PP_3720 | chrR | PP_3720 | PP_4138 | Putative NAD(P)H quinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | 0.706 |
| PP_3720 | ecd | PP_3720 | PP_2490 | Putative NAD(P)H quinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Flavoprotein; Belongs to the flavin oxidoreductase frp family. | 0.874 |
| PP_3720 | mdaB | PP_3720 | PP_4661 | Putative NAD(P)H quinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Modulator of drug activity B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport. | 0.900 |
| arsH | PP_2556 | PP_2715 | PP_2556 | ArsH protein. | Chromate transporter. | 0.499 |
| arsH | chrR | PP_2715 | PP_4138 | ArsH protein. | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | 0.812 |
| arsH | mdaB | PP_2715 | PP_4661 | ArsH protein. | Modulator of drug activity B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport. | 0.438 |
| azoR2 | PP_3720 | PP_4538 | PP_3720 | FMN-dependent NADH-azoreductase 2; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. | Putative NAD(P)H quinone oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.489 |
| azoR2 | chrR | PP_4538 | PP_4138 | FMN-dependent NADH-azoreductase 2; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | 0.780 |
| azoR2 | ecd | PP_4538 | PP_2490 | FMN-dependent NADH-azoreductase 2; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. | Flavoprotein; Belongs to the flavin oxidoreductase frp family. | 0.806 |
| azoR2 | mdaB | PP_4538 | PP_4661 | FMN-dependent NADH-azoreductase 2; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. | Modulator of drug activity B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport. | 0.718 |
| chrR | PP_0101 | PP_4138 | PP_0101 | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | Putative sulfate transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.710 |
| chrR | PP_0718 | PP_4138 | PP_0718 | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | Sulfate transporter. | 0.710 |
| chrR | PP_1407 | PP_4138 | PP_1407 | Chromate reductase; Catalyzes the reduction of quinones. Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR. Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen. This reaction produces transiently a minimal amount of the toxic Cr(5+) species and reactive oxygen species (ROS). Chromate redu [...] | Sulfate transporter. | 0.710 |
