| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_1832 | PP_4155 | PP_1832 | PP_4155 | Putative Oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.742 |
| PP_4155 | PP_1832 | PP_4155 | PP_1832 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Putative Oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.742 |
| PP_4155 | PP_4764 | PP_4155 | PP_4764 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Histone deacetylase family protein. | 0.575 |
| PP_4155 | aroH | PP_4155 | PP_1866 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.711 |
| PP_4155 | bioA | PP_4155 | PP_4984 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.657 |
| PP_4155 | nicC | PP_4155 | PP_3944 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. | 0.728 |
| PP_4155 | nicD | PP_4155 | PP_3943 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | N-formylmaleamate deformylase; Deformylase that catalyzes the conversion of N-formylmaleamic acid to maleamate in the aerobic nicotinate degradation pathway. | 0.645 |
| PP_4155 | nicE | PP_4155 | PP_3942 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Maleate isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate in the aerobic nicotinate degradation pathway. | 0.634 |
| PP_4155 | nicF | PP_4155 | PP_3941 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Maleamate amidohydrolase; Maleamate amidase that transforms maleamate into maleate and ammonia in the aerobic nicotinate degradation pathway. | 0.661 |
| PP_4155 | nicX | PP_4155 | PP_3945 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 2,5-dihydroxypyridine 5,6-dioxygenase; Catalyzes the dioxygenolytic ring cleavage of 2,5- dihydroxypyridine between carbons 5 and 6 generating N-formylmaleamate in the aerobic nicotinate degradation pathway. | 0.631 |
| PP_4155 | pycA | PP_4155 | PP_5347 | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | Pyruvate carboxylase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | 0.672 |
| PP_4764 | PP_4155 | PP_4764 | PP_4155 | Histone deacetylase family protein. | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.575 |
| aroH | PP_4155 | PP_1866 | PP_4155 | Phospho-2-dehydro-3-deoxyheptonate aldolase. | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.711 |
| bioA | PP_4155 | PP_4984 | PP_4155 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.657 |
| bioA | pycA | PP_4984 | PP_5347 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | Pyruvate carboxylase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism. | 0.557 |
| nicC | PP_4155 | PP_3944 | PP_4155 | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. | Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity. | 0.728 |
| nicC | nicD | PP_3944 | PP_3943 | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. | N-formylmaleamate deformylase; Deformylase that catalyzes the conversion of N-formylmaleamic acid to maleamate in the aerobic nicotinate degradation pathway. | 0.995 |
| nicC | nicE | PP_3944 | PP_3942 | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. | Maleate isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate in the aerobic nicotinate degradation pathway. | 0.996 |
| nicC | nicF | PP_3944 | PP_3941 | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. | Maleamate amidohydrolase; Maleamate amidase that transforms maleamate into maleate and ammonia in the aerobic nicotinate degradation pathway. | 0.979 |
| nicC | nicX | PP_3944 | PP_3945 | 6-hydroxynicotinate 3-monooxygenase; Flavin-dependent monooxygenase (FMO) that catalyzes the decarboxylative hydroxylation of 6-hydroxynicotinic acid (6-HNA) to 2,5-dihydroxypyridine (2,5-DHP) with concomitant oxidation of NADH, a step in the aerobic nicotinate degradation pathway. Belongs to the 6-hydroxynicotinate 3-monooxygenase family. | 2,5-dihydroxypyridine 5,6-dioxygenase; Catalyzes the dioxygenolytic ring cleavage of 2,5- dihydroxypyridine between carbons 5 and 6 generating N-formylmaleamate in the aerobic nicotinate degradation pathway. | 0.999 |