STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdpETwo-component system DNA-binding response activator KdpE; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription. (231 aa)    
Predicted Functional Partners:
kdpD
Sensor protein; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
 0.999
kdpA
Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
   
 0.980
kdpB
K+ transporting ATPase, KdpB subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
   
 0.978
PP_2714
Sensor histidine kinase.
 
 0.974
kdpC
Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
   
 0.971
PP_4224
Sensor histidine kinase.
 
 0.961
phoR
Two-component system sensory histidine kinase; Function experimentally demonstrated in the studied strain; receptor; Centralintermediarymetabolism : Phosphorus compounds.
 
 
 0.862
PP_3453
Putative Sensor protein RstB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.771
kup
Probable potassium transport system protein kup; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
     
 0.769
PP_1421
Putative Sensor histidine kinase TctE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.755
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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