Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PP_4168Homologs of previously reported genes of unknown function. (115 aa)    
Predicted Functional Partners:
sixA
Phosphohistidine phosphatase SixA.
  
    0.898
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
    0.826
PP_4164
Alpha/beta hydrolase.
       0.704
PP_4171
Homologs of previously reported genes of unknown function.
       0.686
PP_4172
Homologs of previously reported genes of unknown function.
       0.686
PP_4173
Sensor histidine kinase/response regulator.
       0.686
PP_5077
Homologs of previously reported genes of unknown function.
  
     0.668
PP_1357
Homologs of previously reported genes of unknown function; Unknown function.
  
     0.656
PP_4163
Homologs of previously reported genes of unknown function.
       0.636
fabA
3R-3-hydroxydecanoyl acyl carrier protein (ACP) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
       0.608
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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