STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_4176Putative 5-oxo-L-prolinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (335 aa)    
Predicted Functional Partners:
PP_4177
Homologs of previously reported genes of unknown function; Belongs to the pirin family.
       0.552
PP_0138
Homologs of previously reported genes of unknown function.
  
    0.509
PP_4615
Homologs of previously reported genes of unknown function; Belongs to the PsiE family.
  
    0.509
kefA
Mechanosensitive channel protein, intermediate (smaller, MscS-like) conductance, K+ efflux; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins.
  
    0.464
tolA
Colicin S4 and filamentous phage transport system; Function experimentally demonstrated in the studied strain; transporter; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
    0.443
PP_1968
TetR family transcriptional regulator.
 
     0.427
estP
Esterase EstP; Esterase that catalyzes the hydrolysis of p-nitrophenyl esters of acyl chain lengths C4-C10 and Tween detergents. Has also a pronounced thioesterase activity towards palmitoyl-coenzyme A. Belongs to the 'GDSL' lipolytic enzyme family.
 
     0.412
PP_0251
Homologs of previously reported genes of unknown function.
  
     0.411
lptE
Putative Lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
  
     0.402
PP_1357
Homologs of previously reported genes of unknown function; Unknown function.
  
     0.401
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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