STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_4176Putative 5-oxo-L-prolinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (335 aa)    
Predicted Functional Partners:
PP_1968
TetR family transcriptional regulator.
 
     0.581
PP_4177
Homologs of previously reported genes of unknown function; Belongs to the pirin family.
       0.552
PP_0138
Homologs of previously reported genes of unknown function.
  
    0.532
kefA
Mechanosensitive channel protein, intermediate (smaller, MscS-like) conductance, K+ efflux; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins.
  
    0.515
metH
Cobalamin-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.507
PP_4615
Homologs of previously reported genes of unknown function; Belongs to the PsiE family.
  
     0.507
PP_0092
Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein.
   
    0.458
tolA
Colicin S4 and filamentous phage transport system; Function experimentally demonstrated in the studied strain; transporter; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
    0.439
PP_0251
Homologs of previously reported genes of unknown function.
  
     0.411
estP
Esterase EstP; Esterase that catalyzes the hydrolysis of p-nitrophenyl esters of acyl chain lengths C4-C10 and Tween detergents. Has also a pronounced thioesterase activity towards palmitoyl-coenzyme A. Belongs to the 'GDSL' lipolytic enzyme family.
 
     0.411
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.