Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pvdTPyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (654 aa)    
Predicted Functional Partners:
pvdR
ABC export system, membrane fusion protein; Function of strongly homologous gene; transporter; Transport and binding proteins; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 0.999
ompQ
Outer membrane pyoverdine efflux protein; Function of strongly homologous gene; transporter; Transport and binding proteins.
 
 0.999
tolC
Agglutination protein.
 
 
 0.912
pvdO
Pyoverdine biosynthesis related protein; Function of strongly homologous gene; enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis.
  
 
 0.893
PP_1647
Homologs of previously reported genes of unknown function.
 
 
   0.879
PP_0715
Outer membrane efflux protein.
  
 
 0.875
PP_0805
Outer membrane efflux protein.
  
 
 0.874
PP_1798
Outer membrane efflux protein.
  
 
 0.850
PP_4923
Outer membrane efflux protein.
  
 
 0.850
ttgA
Probable efflux pump periplasmic linker TtgA; Probable periplasmic linker protein component of the TtgABC efflux pump with unknown specificity; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.847
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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