Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_4231Putative Xanthine dehydrogenase accessory factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (323 aa)    
Predicted Functional Partners:
PP_4230
Homologs of previously reported genes of unknown function.
 
  
 0.968
PP_4233
Putative Oxidoreductase, small subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.956
PP_4234
Aldehyde oxidase and xanthine dehydrogenase.
 
  
 0.928
PP_2483
Homologs of previously reported genes of unknown function.
 
  
 0.869
iorA-II
Isoquinoline 1-oxidoreductase subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.822
iorA-I
Isoquinoline 1-oxidoreductase subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.821
nicA
Nicotinate dehydrogenase subunit A; Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6- hydroxynicotinate (6HNA).
 
  
 0.813
PP_3622
Putative Isoquinoline 1-oxidoreductase, beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.809
PP_2478
Putative Isoquinoline 1-oxidoreductase, beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.804
paoA
Promiscuous aromatic aldehyde dehydrogenase, 2Fe-2S subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.799
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (24%) [HD]