STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbGPeriplasmic protein disulfide isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (252 aa)    
Predicted Functional Partners:
dsbD-II
Thiol/disulfide interchange protein 2; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
 
 
 0.990
PP_4236
Putative Thiol:disulfide interchange protein dsbE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.971
dsbB
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity). Belongs to the DsbB family.
  
 
 0.932
dsbD-I
Thiol/disulfide interchange protein 1; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.926
PP_4238
Homologs of previously reported genes of unknown function.
     
 0.917
dsbC
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
     
 0.907
PP_4224
Sensor histidine kinase.
 
    0.702
PP_0052
Beta-lactamase domain protein, putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.691
ssuE
NAD(P)H-dependent FMN reductase subunit; Probably forms a two-component reduced flavin mononucleotide- dependent monooxygenase by binding to SsuD. Required for growth on aliphatic sulfonates or methionine but not arylsulfonates (By similarity); Belongs to the SsuE family.
      
 0.653
PP_2772
Putative Monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.653
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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